Lidokain Spay instructions for use, how to take?

Lidocaine Spray is a widely utilized topical (local) anesthetic agent that provides rapid and effective temporary pain relief. Its popularity stems from its convenience of use and fast onset of action.

Composition and Pharmacological Action

Active Ingredient: The primary and sole active component of the preparation is lidocaine (usually in its hydrochloride form). Lidocaine belongs to the pharmacological group of local anesthetics known as the amide type.

Mechanism of Action: Understanding how Lidocaine Spray works requires a brief dive into the neurophysiology of pain. Pain is a signal transmitted by nerve fibers to the brain as electrical impulses (action potentials). This process is critically dependent on the movement of sodium ions (Na+) across the membrane of the nerve cell (neuron).

Lidocaine acts by temporarily blocking specific voltage-gated sodium channels on the membrane of nerve endings at the site of application. When these channels are blocked, sodium ions cannot enter the cell, making it impossible for the electrical impulse to arise and propagate. In essence, lidocaine "cuts" the wire through which the pain signal travels to the brain. As a result, even though the stimulus (e.g., a needle) is still present, the brain does not receive the "pain message," and the patient experiences numbness. This effect is completely reversible; as the drug is metabolized, nerve function is fully restored.

Excipients (Auxiliary Components): The spray formula also includes auxiliary ingredients that ensure its efficacy, stability, and safety. These may include:

• Solvents (e.g., ethanol, propylene glycol, purified water) to dissolve the lidocaine.

• Preservatives (e.g., methylparaben) to prevent bacterial growth.

• pH regulators (e.g., sodium hydroxide) to maintain an optimal pH, which is crucial for lidocaine's activity.

• Occasionally, flavoring agents (e.g., mint) to improve the taste when used in the oral cavity.

Form of Release and Packaging

Lidocaine Spray is typically marketed as a liquid solution contained in glass or plastic bottles equipped with a metered-dose pump (atomizer). This delivery system is a key advantage. The dispenser provides a precise, metered spray(measured in milligrams of lidocaine per actuation), which allows for dose control and reduces the risk of overdose.

The concentration of the active ingredient may vary (e.g., 8% or 10%), as can the total volume of the bottle (e.g., 25 mL, 38 g, 50 mL), depending on the manufacturer and target market. The spray creates a fine mist that evenly coats the desired area of skin or mucous membrane.

Lidocaine Spray: Detailed Indications for Use

The spectrum of the drug's application is very broad due to its ability to rapidly numb superficial tissues.

1. Dentistry: This is one of its most common applications. The spray is used for:

   • Numbing the injection site before administering a primary anesthetic injection.

   • Suppressing the gag reflex during dental impressions or X-rays.

   • Superficial anesthesia of the gums before professional cleaning, scaling, or treatment of gingivitis.

   • Temporary pain relief for the extraction of loose deciduous (baby) teeth.

2. Cosmetology and Dermatology:

   • Numbing the skin before injection procedures (mesotherapy, biorevitalization, filler injections).

   • Alleviating pain during hair removal (especially laser or waxing in sensitive areas like the bikini line).

   • Pain relief before tattooing or permanent makeup procedures.

   • Reducing discomfort during body piercing.

3. Superficial Skin Injuries:

   • Providing pain relief for mild sunburns (first-degree) or minor thermal burns.

   • Numbing abrasions, scrapes, or itchy insect bites.

4. Medical Examinations and Intimate Procedures:

   • Otorhinolaryngology (ENT): Numbing the nasal passages or throat before endoscopy, intubation, or other manipulations.

   • Gynecology and Urology: Superficial anesthesia before the insertion of catheters, colposcopy, or other diagnostic procedures.

   • Proctology: Anesthesia for anoscopy or to alleviate the symptoms of hemorrhoids.

5. Management of Premature Ejaculation (PE):

   • This is a specific indication. Lidocaine Spray, when applied to the glans penis 10-15 minutes before intercourse, reduces its hypersensitivity. This allows the man to better control the timing of ejaculation and prolong the duration of sexual intercourse.

Dosage and Detailed Method of Application

Step 1: Preparation

• The area of skin or mucous membrane must be thoroughly cleaned of dirt, oils, or mucus. This ensures better contact between the drug and the surface.

• Dry the area. Water can dilute the preparation and reduce its effectiveness.

• Allergy Test: On first use, it is vital to perform a patch test. Apply one spray to a small, inconspicuous area of skin (e.g., the inner wrist). Wait 15-20 minutes. If severe redness, a rash, intense itching, or swelling (hives) appears, use of the product is contraindicated.

Step 2: Application

• Hold the bottle upright, with the nozzle pointed at the area.

• Spray from the recommended distance of 5-10 cm (2-4 inches). A closer distance will create a stream and uneven coverage, while spraying from too far will cause the aerosol to disperse in the air.

• Dosage is critical. Typically, 1-3 actuations (sprays) of the dispenser are sufficient for one area. Always use the minimum effective dose. The exact amount depends on the size of the area to be numbed and the physician's recommendations. Exceeding the dose is dangerous.

Step 3: Post-Application

• The anesthetic effect (numbness) usually begins quickly, within 1-2 minutes.

• After the procedure is complete (e.g., hair removal or dental work), the residue of the drug can be washed off with warm water to avoid prolonged numbness or accidental transfer to other areas (like the eyes).

What are the Contraindications for Lidocaine Spray?

1. Allergy (Hypersensitivity): An absolute contraindication. This applies not only to lidocaine but also to other amide-type local anesthetics (e.g., bupivacaine, mepivacaine). If a patient has a history of allergy to any of these, the spray must not be used.

2. Severe Liver Impairment: Lidocaine is metabolized (broken down) primarily by the liver. In severe hepatic failure (e.g., cirrhosis), the liver cannot process lidocaine effectively. This leads to its accumulation in the blood to toxic levels.

3. Broken or Compromised Skin: Do not, under any circumstances, apply the spray to deep wounds, open ulcers, or severely damaged (e.g., weeping) skin. The skin acts as a barrier. When this barrier is absent, lidocaine is absorbed into the systemic circulation instantly and in uncontrolled amounts, causing severe overdose.

4. Pregnancy and Breastfeeding: Lidocaine crosses the placental barrier and is excreted in breast milk. Although the risk is considered low with topical application, its use is only justified if prescribed by a doctor who determines that the potential benefit to the mother outweighs the potential risk to the fetus or infant.

5. Pediatric Use: Use in children (especially young children) must be done with extreme caution and only under a doctor's supervision. Children are more susceptible to systemic toxicity due to their lower body mass. The dose must be calculated very precisely.

Possible Side Effects

Local Reactions (Common and Expected):

• Temporary redness (erythema), mild irritation, or a stinging/burning sensation at the application site. This usually resolves on its own.

• Numbness (paresthesia): This is the intended therapeutic effect but can be uncomfortable (e.g., numbness of the tongue or throat after dental use, which can lead to a risk of biting oneself or choking).

Allergic Reactions (Uncommon but Serious):

• Cutaneous (Skin) signs: Hives (urticaria, a welt-like rash), itching (pruritus).

• Angioedema: Swelling of the face, lips, tongue, or throat, which can be life-threatening if it obstructs the airway.

• Anaphylactic Shock: The most severe reaction (a rapid drop in blood pressure, bronchospasm, loss of consciousness). This requires immediate emergency medical attention.

Systemic Toxicity (From Overdose or Rapid Absorption): This is the most dangerous potential side effect. If too much lidocaine enters the bloodstream, it affects the central nervous system (CNS) and the cardiovascular system.

• CNS Effects: Dizziness, lightheadedness, drowsiness, anxiety, ringing in the ears (tinnitus), a metallic taste in the mouth, blurred vision, tremors, disorientation. In severe cases: seizures and respiratory depression.

• Cardiovascular Effects: Low blood pressure (hypotension), slow heart rate (bradycardia), abnormal heart rhythms (arrhythmias).

If any systemic symptoms (dizziness, nausea, ringing in the ears) appear, use must be stopped immediately, and medical help sought.

Special Precautions and Safety Measures

1. Avoid Eye Contact: Do not allow the spray to enter the eyes. It can cause severe chemical irritation. Furthermore, anesthetizing the cornea is dangerous because you will not be able to feel if a foreign object enters the eye, potentially leading to corneal abrasion. If accidental contact occurs, immediately and thoroughly rinse the eyes with clean water for 10-15 minutes.

2. Do Not Exceed the Dose: Always follow the instructions or a doctor's recommendation for the maximum number of sprays per application and per day.

3. Use on Mucous Membranes: Absorption of lidocaine from mucous membranes (mouth, throat, genitals) is much faster and more complete than from intact skin. This increases the risk of systemic toxicity. Be especially cautious when applying to these areas.

Storage Conditions for Lidocaine Spray

• Store the bottle in a dry, cool place, protected from light. Direct sunlight can degrade the active ingredient.

• The optimal storage temperature is not exceeding 25°C (77°F). Do not freeze.

• Most importantly: Keep the product out of the reach of children. Accidental ingestion or excessive spraying by a child can be fatal.

• Expiration Date: Clearly marked on the packaging. Do not use the product after this date, as its efficacy and safety are not guaranteed.

Important Concluding Information

Lidocaine Spray is an effective and convenient tool for local pain relief. However, it is not "safe water." It is a serious medication with clear contraindications and the risk of dangerous side policies if used improperly. You must consult with a physician before using this product. A doctor can determine if this product is safe for you, rule out potential contraGindications and drug interactions, and prescribe the correct dosage. Self-medication can be hazardous to your health.