POXET

What is POXET?

The drug POXET is a modern highly effective medicine developed to solve delicate problems in the field of men's sexual health. This medication belongs to the pharmacological group of selective serotonin reuptake inhibitors and is intended for the therapy of premature ejaculation in men of reproductive age. The drug is available in the form of oral film-coated tablets, which ensures ease of use and rapid absorption of the active component in the gastrointestinal tract. The production of the medicine is carried out according to modern pharmaceutical standards, which guarantees high quality, compliance with international safety requirements, and a stable therapeutic result.

The main task of the drug POXET is to restore control over the ejaculation process, which allows to significantly prolong the duration of intercourse and improve the quality of intimate life. Ejaculation disorder is a common pathology that occurs due to neurobiological factors, a decrease in serotonin levels in the central nervous system, or psycho-emotional overstrain. Thanks to its targeted effect on the neural receptors of the brain, this drug helps to overcome physiological and psychological barriers. Systematic or symptomatic use of the medicine allows a man to regain confidence in his own strength and reduce anxiety associated with the expectation of a possible failure.

The drug POXET differs from other sedatives or antidepressants by its rapid onset of action and short half-life in the body, which makes it an ideal choice for use immediately before intimacy. The official manufacturer of this pharmaceutical product is the leading company Centurion Laboratories, which has established itself as a reliable supplier of high-quality generic drugs. The medication belongs to the category of products for improving potency and regulating ejaculation, providing a comprehensive approach to solving disorders of the genitourinary system. Before start using this product, a consultation with a specialist is absolutely necessary to exclude contraindications and select the optimal therapy regimen.

What is POXET prescribed for?

The main indication for the use of the drug POXET is primary or acquired premature ejaculation in men aged 18 to 64 years. This condition is characterized by persistent or recurrent ejaculation with minimal sexual stimulation before, during, or shortly after penetration. The use of this pharmaceutical drug allows to significantly correct this process, extending the latent time of intravaginal ejaculation several times. Along with this, the level of psychological discomfort, which inevitably arises in a man and his partner against the background of intimate disorders, is significantly reduced.

In addition to eliminating a purely physiological symptom, POXET is prescribed for improving control over ejaculation and reducing anxiety levels. Very often, a premature finish becomes the cause of the development of a secondary psychogenic performance anxiety syndrome, which worsens erection and reduces libido. Thanks to pharmacological support, a man gets the opportunity to independently regulate the moment of ejaculation, which has a positive effect on the emotional state and harmonization of relationships in a couple. The drug acts gently, without causing addiction and without suppressing natural satisfaction from sexual contact.

Also, the drug POXET can be recommended as part of complex therapy of sexual dysfunctions accompanied by chronic pelvic pain syndrome or increased sensitivity of the genitals. Urologists and andrologists prescribe this medication to patients who want to improve the quality of their sexual life and feel complete liberation. It is important to understand that the drug is effective only in the presence of adequate sexual stimulation, as it is not a libido stimulant in the literal sense of the word. The individual reaction of the body to therapy may differ depending on the severity of the pathology and the presence of concomitant diseases.

Composition and active components of POXET

The main active component of the drug POXET is dapoxetine in the form of hydrochloride, which is a short-acting selective serotonin reuptake inhibitor. Dapoxetine selectively blocks serotonin transporters, increasing its concentration in the synaptic cleft of neurons of the central nervous system. This leads to an increase in the action of serotonin on pre- and postsynaptic receptors responsible for delaying impulses in the sympathetic nervous system. As a result, the ejaculation reflex is inhibited at the level of the brain and spinal cord, which allows to prolong the duration of sexual intercourse.

Each tablet of POXET also contains excipients that ensure the stability of the formula, proper release of the active component, and ease of absorption. Among them are microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, magnesium stearate, and a special film coating that protects the stomach from irritation. All components meet strict pharmaceutical standards of purity and pharmacological safety. They contribute to the rapid disintegration of the tablet in the digestive tract and the maximum bioavailability of dapoxetine within a short period of time after administration.

Dosage of POXET

The standard starting dosage of POXET is 30 mg of dapoxetine, which corresponds to half of a 60 mg tablet, unless otherwise prescribed by a doctor. The drug is taken 1–3 hours before the intended sexual contact, washed down with plenty of water. If the therapeutic effect of the 30 mg dose is insufficient and side reactions are absent, the doctor may recommend increasing the dose to the maximum — 60 mg per day. It is strictly forbidden to exceed the specified dosage or take the drug more than once every 24 hours, as this increases the risk of developing undesirable effects.

The duration of the use of POXET is determined by the doctor individually after a detailed diagnosis and evaluation of the effectiveness of the therapy. The drug is intended mainly for "on-demand" use, that is, immediately before intercourse, and not for daily scheduled courses. 4 weeks after the start of treatment (or after taking at least 6 doses), the doctor must evaluate the benefit-risk ratio to make a decision on the feasibility of further use of the product. For elderly patients or individuals with minor renal impairment, dose adjustment is usually not required, but additional medical supervision is necessary.

How to take POXET correctly?

The POXET tablet should be swallowed whole, without chewing or crushing, to prevent a bitter taste and ensure proper release of the substance. It is recommended to wash the drug down with a full glass of clean drinking water at room temperature to speed up its absorption and reduce the risk of dizziness. The medication can be taken regardless of food intake, but fatty food can slightly delay the onset of its action. To achieve the optimal result, it is better to refrain from excessive consumption of heavy meals immediately before taking the tablet.

If the patient missed the time of administration or sexual contact did not take place, there is no need to take POXET additionally, as the product is not intended for daily cumulative use. The main precaution is that dehydration of the body should be avoided while taking the medication, so it is recommended to maintain an adequate water balance. If symptoms of a pre-fainting state (dizziness, nausea, increased sweating) occur during administration, the patient should immediately lie down or sit down with their head lowered between their knees until the unpleasant sensations completely disappear.

Side effects of POXET

The most common side effects when using POXET are nausea, dizziness, headache, diarrhea, and insomnia. Patients may also experience increased fatigue, anxiety, hot flashes, ringing in the ears, or nasal congestion. Usually, these symptoms are mild or moderate, occur at the beginning of therapy, and pass on their own as the substance is eliminated from the body. To minimize the risk of nausea, it is recommended to wash the tablet down with plenty of water and avoid taking the drug on an empty stomach.

Rare but more serious adverse reactions include orthostatic hypotension, fainting (syncope), bradycardia or tachycardia, mood changes, euphoria, or depressive states. In case of a sharp drop in blood pressure or loss of consciousness, it is necessary to stop taking the medication and seek medical help. If seizures, allergic reactions in the form of hives or Quincke's edema, as well as visual disturbances occur, you should immediately call an ambulance. Remember that the individual reaction of the body can be unpredictable, so monitoring your own well-being is mandatory.

Contraindications of POXET

The use of the medication POXET is strictly contraindicated in patients with hypersensitivity to dapoxetine or any other component of the drug. The drug is prohibited for use by persons with severe heart pathologies, such as heart failure (NYHA classes II–IV), conduction disorders (AV block of II-III degree), sick sinus syndrome, coronary heart disease, or the presence of an artificial pacemaker. Also, an absolute contraindication is moderate and severe hepatic impairment, as this disrupts the metabolism of dapoxetine and leads to its toxic accumulation in tissues.

The product POXET is not intended for use in women, children, and adolescents under 18 years of age, as well as patients over 65 years of age due to the lack of sufficient clinical data. Relative contraindications are manic states, severe depression, epilepsy with an unstable course, blood clotting disorders, and severe kidney diseases. Before starting therapy, the patient must undergo a complete examination by a doctor to exclude latent diseases of the cardiovascular and nervous systems, in which the use of selective serotonin reuptake inhibitors is life-threatening.

Interaction of POXET with other drugs and alcohol

Concomitant use of POXET with medications that affect the central nervous system requires special caution and strict medical supervision. The drug is forbidden to be combined with monoamine oxidase inhibitors (MAOIs), thioridazine, lithium, tryptophan, tramadol, St. John's wort, and other antidepressants (SSRIs, SNRIs). At least 14 days must pass between stopping the intake of these products and starting the use of dapoxetine. Interaction with potent CYP3A4 inhibitors, such as ketoconazole, itraconazole, ritonavir, and atazanavir, which significantly increase the concentration of dapoxetine in blood plasma, is also dangerous.

It is strictly not recommended to combine POXET with the consumption of alcoholic beverages or recreational drugs. Ethanol increases the neurotoxic effect of dapoxetine, significantly increases the risk of dizziness, drowsiness, slowing of speed reactions, and occurrence of fainting states. In addition, alcohol itself worsens sexual function and reduces the therapeutic efficacy of the medication. During treatment with this drug, one should refrain from driving vehicles and working with potentially dangerous machinery, as sudden disturbances in concentration, vision, and coordination of movements are possible.

Where to buy POXET in Ukraine

You can buy POXET in Ukraine in specialized pharmaceutical establishments or through certified online pharmacy platforms that carry out licensed trade in medicines. The drug is sold in original blisters, which guarantees its authenticity and protection against counterfeits. The price of the medication may vary depending on the dosage and the number of tablets in the package, making it affordable for a wide range of patients. When buying the product online, you should choose verified pharmacy chains that comply with transport conditions and guarantee the confidentiality of order delivery throughout the country.

Store POXET in its original packaging in a dry, dark place out of reach of children at a temperature not exceeding 25 °C. Do not use the medication after the expiration date printed on the cardboard box and blister. Remember that self-medication can be harmful to your health, so before purchasing and using this medicine, be sure to consult a urologist or andrologist. Only a qualified specialist will be able to correctly establish a diagnosis, calculate a safe dose, and make sure there are no contraindications.