CENFORCE D EXTRA POWER
- Manufacturer:
- Centurion Laboratories
- Active ingredient
- Sildenafil + Dapoxetine
- Dosage
- 100 mg + 100 mg
- Best before date
- Until 2028
- Reception
- 1.3 hours before the act
- Time of action
- Up to 5-6 hours
- Daily dose
- 1 tablet
- Compatibility with alcohol
- No
Available product types:
What is CENFORCE D EXTRA POWER?
CENFORCE D EXTRA POWER is a combination drug designed for the correction of erectile dysfunction and premature ejaculation in men. The product is manufactured by the Indian pharmaceutical company Centurion Laboratories, which specializes in producing high-quality generics for the treatment of sexual disorders. The drug belongs to the group of phosphodiesterase type 5 (PDE-5) inhibitors combined with a selective serotonin reuptake inhibitor. The release form is hard gelatin capsules or film-coated tablets, which ensure rapid absorption of the active substances in the gastrointestinal tract.
The pharmacological action of CENFORCE D EXTRA POWER is directed at simultaneously resolving two key intimate issues: insufficient penile rigidity and uncontrolled rapid ejaculation. This dual mechanism allows a man not only to achieve a firm erection but also to significantly extend the duration of sexual intercourse. The drug is not a hormonal agent and does not directly affect libido, but it creates optimal physiological conditions for complete sexual contact. The therapeutic effect develops only in the presence of natural sexual arousal, which distinguishes this product from central nervous system stimulants.
Centurion Laboratories has established itself as a manufacturer that adheres to international GMP (Good Manufacturing Practice) quality standards. Each batch of CENFORCE D EXTRA POWER undergoes multi-stage testing for purity and stability of active components. The drug is widely represented in the pharmaceutical markets of Eastern Europe and Asia, where it has received positive feedback from both patients and practicing urologists. It is important to understand that this is a prescription medication, and its use should take place under the supervision of a physician following appropriate examination.
What is CENFORCE D EXTRA POWER prescribed for?
The main indications for the use of CENFORCE D EXTRA POWER are conditions that significantly reduce the quality of a man's sex life. The primary indication is erectile dysfunction of varying severity, manifested by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. This disorder can have vascular, neurogenic, psychogenic, or mixed origins. Sildenafil in the composition of the drug acts specifically on the vascular component, relaxing the smooth muscle of the cavernous bodies and increasing blood flow to the penis.
The second key indication is premature ejaculation, defined as persistent or recurrent ejaculation with minimal sexual stimulation before, during, or shortly after penetration. Dapoxetine in CENFORCE D EXTRA POWER increases the threshold for the ejaculatory reflex, allowing a man to control the moment of climax. Clinical studies show an increase in intravaginal ejaculatory latency time by an average of three times compared to placebo. This allows the couple to achieve mutual sexual satisfaction and reduces psychological tension associated with sexual intimacy.
The drug can also be recommended for men with a combined form of sexual dysfunction, where erectile insufficiency is accompanied by anxiety regarding the duration of sexual intercourse. In such cases, the complex action of the two active components provides a synergistic effect: a stable erection reduces the fear of failure, while control over ejaculation increases self-confidence. CENFORCE D EXTRA POWER is not intended for use by women or individuals under 18 years of age. Prior to starting therapy, organic causes of erectile dysfunction, particularly cardiovascular disease and diabetes mellitus, must be ruled out.
Composition and active ingredients of CENFORCE D EXTRA POWER
Each tablet of CENFORCE D EXTRA POWER contains two active substances in therapeutically balanced doses. Sildenafil citrate at a dose of 100 mg is a potent selective phosphodiesterase type 5 inhibitor that enhances the relaxing effect of nitric oxide in the cavernous bodies of the penis. The mechanism of action involves blocking the PDE-5 enzyme, which prevents the premature degradation of cyclic guanosine monophosphate (cGMP). High levels of cGMP provide prolonged vasodilation and engorgement of the erectile tissue with blood, manifesting as a firm erection during sexual stimulation.
Dapoxetine hydrochloride at a dose of 60 mg belongs to the class of short-acting selective serotonin reuptake inhibitors. It blocks the serotonin transporter at the neuronal synaptic cleft, increasing the concentration of this neurotransmitter in the central nervous system. Increased serotonergic activity in brainstem nuclei, particularly the paragigantocellular nucleus, leads to a delay in the ejaculatory reflex. Unlike SSRI antidepressants, dapoxetine has a rapid onset of action and a short elimination half-life, making it suitable for as-needed use rather than continuous administration.
Excipients of CENFORCE D EXTRA POWER include microcrystalline cellulose, croscarmellose sodium, magnesium stearate, lactose monohydrate, and film-coating colorants. These substances ensure the proper stability of the tablet, its disintegration in the stomach, and the uniform release of active pharmaceutical ingredients. Patients with lactose intolerance should take the presence of this component into account. The drug is gluten-free, allowing its use by individuals with celiac disease.
Dosage of CENFORCE D EXTRA POWER
The standard recommended dose of CENFORCE D EXTRA POWER for adult men is one tablet per day, taken 1–3 hours before planned sexual activity. The maximum daily dose should not exceed one tablet, as exceeding the dosage significantly increases the risk of side effects, especially those related to the cardiovascular system. The drug is not intended for continuous daily use; it is used on an as-needed basis when sexual contact is anticipated. The frequency of administration is limited to once every 24 hours.
For elderly patients (over 65 years of age), dose adjustment is usually not required; however, it is recommended to start therapy with the minimum effective dose under a doctor's supervision. Men with mild to moderate hepatic impairment should use the drug with caution, as the metabolism of both active components involves liver enzymes. In severe hepatic impairment, the use of CENFORCE D EXTRA POWER is contraindicated. Patients with severe renal impairment are also advised to avoid this combination drug.
The duration of the treatment course is determined individually depending on the nature of the sexual disorder and the response to therapy. In most cases, the drug is used episodically without forming dependence or tolerance. If after several attempts the therapeutic effect is absent or insufficiently pronounced, it is necessary to consult a physician to review the diagnosis and possibly adjust the treatment regimen. Self-increasing the dose is strictly prohibited.
How to take CENFORCE D EXTRA POWER correctly?
The CENFORCE D EXTRA POWER tablet should be swallowed whole, without chewing or crushing, with a sufficient amount of water (at least 200 ml). Food intake, especially high-fat meals, can delay the absorption of sildenafil and postpone the onset of action by 30–60 minutes. To achieve predictable results, it is recommended to take the medication on an empty stomach or after a light, low-fat snack. The optimal time of administration is 60–90 minutes before anticipated intimacy, allowing peak plasma concentrations of active substances to be reached precisely at the time of sexual activity.
If a dose was missed but sexual contact did not occur, a double dose should not be taken the next time. CENFORCE D EXTRA POWER works only under conditions of sexual arousal, so after taking the tablet, natural stimulation is required to trigger the physiological mechanism of erection. The drug does not cause a spontaneous erection without erotic stimulation. The duration of action of sildenafil is up to 4–6 hours, while the effect of dapoxetine on delaying ejaculation persists for 3–4 hours after intake.
During CENFORCE D EXTRA POWER therapy, it is important to avoid consuming grapefruit juice, as it inhibits the CYP3A4 enzyme, which may lead to increased plasma concentrations of sildenafil and a higher risk of adverse reactions. Patients should also refrain from driving vehicles or operating complex machinery until their individual response is established, as the medication can cause dizziness or visual disturbances. If an erection lasts longer than 4 hours, immediate medical attention must be sought.
Side effects of CENFORCE D EXTRA POWER
The most common side effects of CENFORCE D EXTRA POWER are headache, flushing, dizziness, and nasal congestion. These symptoms are related to the vasodilatory action of sildenafil and are usually mild or moderate in nature, resolving within a few hours after administration. Gastrointestinal effects may include dyspepsia, nausea, abdominal pain, and diarrhea. Dapoxetine can cause increased sweating, anxiety, insomnia, or somnolence. Most patients tolerate the drug well, and the incidence of adverse reactions decreases with repeated use as the body adapts.
Uncommon side effects include visual disturbances (increased sensitivity to light, blurred vision, changes in color perception), tachycardia, increased blood pressure, muscle pain, and skin rashes. Rare but serious complications include priapism (a prolonged, painful erection), sudden loss of hearing or vision, heart attack, and immediate-type allergic reactions. The occurrence of any of these symptoms requires immediate discontinuation of the drug and emergency medical evaluation.
An individual's response to CENFORCE D EXTRA POWER may vary significantly depending on age, cardiovascular health, liver and kidney function, and concomitant use of other medications. Patients with hypotension or uncontrolled hypertension are at increased risk for hemodynamic instability. Before taking the medication for the first time, a consultation with a doctor is mandatory to evaluate the risk-benefit ratio in each specific case.
Contraindications of CENFORCE D EXTRA POWER
Absolute contraindications to the use of CENFORCE D EXTRA POWER include the concomitant use of nitrates or nitric oxide donors in any medicinal forms. Combining sildenafil with nitroglycerin, isosorbide dinitrate, or other nitrates can cause a life-threatening drop in blood pressure. The drug is also contraindicated in men with severe cardiovascular diseases: recent myocardial infarction (within 90 days), unstable angina, severe heart failure, and uncontrolled arrhythmias. For patients with vision loss due to non-arteritic anterior ischemic optic neuropathy, the use of PDE-5 inhibitors is prohibited.
Relative contraindications include anatomical deformation of the penis (Peyronie's disease, angiofibroma, cavernosal fibrosis), conditions that increase the risk of priapism (sickle cell anemia, leukemia, multiple myeloma), and acute peptic ulcer disease. CENFORCE D EXTRA POWER is not intended for use by women, children, or adolescents under 18 years of age. In men with severe hepatic impairment (Child-Pugh Class C) and end-stage renal disease, the drug is contraindicated due to the risk of active metabolite accumulation.
Special caution is required when using the drug in elderly patients with polymorbidity who take multiple medications simultaneously. Before prescribing CENFORCE D EXTRA POWER, a physician must conduct a complete physical examination, take a history regarding cardiovascular events, and assess the patient's capacity to tolerate the physical exertion associated with sexual activity. Self-medication without prior medical consultation can lead to serious complications, especially in individuals with latent forms of ischemic heart disease.
Interaction of CENFORCE D EXTRA POWER with other drugs and alcohol
CENFORCE D EXTRA POWER enters into clinically significant interactions with a number of medications. Combination with nitrates is strictly prohibited (nitroglycerin, isosorbide dinitrate, isosorbide mononitrate) as well as with nitric oxide donors, as this leads to a dangerous drop in blood pressure. CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, clarithromycin) increase plasma concentrations of sildenafil and dapoxetine, requiring dose reduction or complete avoidance of the combination. CYP3A4 inducers (rifampicin, carbamazepine, phenytoin), on the contrary, reduce the efficacy of the drug. Concomitant use of alpha-blockers (doxazosin, tamsulosin) can cause orthostatic hypotension.
Alcohol consumption during CENFORCE D EXTRA POWER therapy is not recommended, as ethanol potentiates the vasodilatory effect of sildenafil and enhances the sedative effect of dapoxetine. Even moderate amounts of alcohol can cause significant dizziness, tachycardia, and a reduced ability to concentrate. Furthermore, alcohol itself is a central nervous system depressant and can impair erectile function, negating the therapeutic effect of the drug. Driving vehicles after taking CENFORCE D EXTRA POWER is possible only after the patient ensures there are no individual reactions impairing psychomotor functions.
Where to buy CENFORCE D EXTRA POWER in Ukraine
You can purchase CENFORCE D EXTRA POWER in Ukraine at licensed pharmacy establishments authorized to sell prescription drugs. Since the product belongs to the category of prescription medications, a valid prescription from a urologist, andrologist, or family physician must be obtained prior to purchase. Online pharmacies also offer this drug with reservation and delivery options; however, it is important to verify licensing and avoid dubious sellers offering products without a prescription or at abnormally low prices.
CENFORCE D EXTRA POWER should be stored in a dry place protected from light at a temperature not exceeding 25°C. The shelf life is typically 24–36 months from the date of manufacture indicated on the packaging. The medication must be kept out of the reach of children. Before use, it is essential to check the integrity of the blister packaging and ensure the labeling corresponds to original Centurion Laboratories products. If any doubts arise regarding the quality or origin of the product, refrain from taking it and consult a pharmacist.
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