Buy Avanafil 50 mg in Ukraine

Avanafil 50 mg: The Minimum Effective Dose for a Safe Start

Avanafil 50 mg (e.g., in medications Stendra 50 mg or generics Avana 50) is a medication containing 50 mg of Avanafil. This is the minimum recommended therapeutic dose of the new-generation PDE5 inhibitor. It is intended for men who are starting treatment for erectile dysfunction (ED) or who are sensitive to side effects, offering a unique combination of ultra-fast onset and high selectivity.

What is Avanafil 50 mg?

Avanafil 50 mg is an oral medication containing 50 mg of Avanafil.

Indication and 50 mg Dosage

The 50 mg dose is the recommended starting dose in some cases, as well as the minimum effective dose. It is ideal for:

• Men starting treatment: Allows assessment of the body's individual response with minimal risk.

• Patients with mild ED: When 100 mg is an excessive dose.

• Men sensitive to side effects: If 100 mg caused headaches or flushing, 50 mg is a better alternative.

• Elderly patients: (Over 65), who often require lower dosages.

Key Advantages of Avanafil

Avanafil has two unique pharmacokinetic profiles:

1. Ultra-Fast Start: This is the fastest PDE5 inhibitor. The effect can begin in as little as 15-20 minutes after intake (compared to 30-60 minutes for other drugs).

2. High Selectivity: Avanafil acts very precisely on PDE5, which ensures a significantly lower risk of specific side effects (vision problems, back pain).

Detailed Mechanism of Action of Avanafil

The mechanism of action of Avanafil is identical to other PDE5 inhibitors.

1. Trigger: Sexual arousal causes the release of nitric oxide (NO).

2. Erectile Cycle: NO stimulates the formation of cyclic GMP (cGMP), which relaxes the smooth muscles of the penile blood vessels, ensuring a powerful blood flow.

3. PDE5 Blockade: Avanafil (at 50 mg) blocks the enzyme that degrades cGMP. This allows cGMP to persist longer, ensuring a stable erection in response to stimulation.

Key takeaway: Avanafil 50 mg provides a rapid "window" of readiness (about 5-6 hours), but sexual arousal is always required to achieve an erection.

Instructions for Using Avanafil (50 mg)

Strict adherence to the instructions is necessary for safety and maximum efficacy.

Dosage and Timing of Intake

• Dosage: 50 mg (one tablet) – is the standard starting dose.

• Frequency of Intake: Avanafil should be taken no more than once per day.

• Method: Swallow the tablet whole with water.

• Timing: Take 15–30 minutes before planned sexual activity.

Influence of Food and Alcohol

• Food: Unlike Sildenafil, taking Avanafil with a moderately high-fat meal does not significantly affect the onset of action.

• Alcohol: It is not recommended to combine Avanafil with excessive amounts of alcohol (more than 3 servings), as this can increase the risk of dropping blood pressure and dizziness.

Critical Contraindications

The list of contraindications related to the vasodilating effect is strict.

• Interaction with Nitrates: Absolutely forbidden! Taking Avanafil with any form of organic nitrates (Nitroglycerin) or nitric oxide donors ("poppers") causes a life-threatening drop in blood pressure.

• Severe Cardiovascular Diseases: Recent heart attack or stroke (within 6 months), severe heart failure, unstable angina.

• Blood Pressure: Persistent hypotension (pressure < 90/50 mmHg) or uncontrolled hypertension.

• Liver and Kidneys: Severe hepatic or renal failure.

Side Effects of Avanafil (50 mg)

The 50 mg dose has the best safety profile and a minimal risk of side effects.

• Common: Headache, facial flushing, nasal congestion (usually less pronounced than at 100 mg).

• Specific (Very Rare): Avanafil very rarely causes visual disturbances ("blue haze") or back pain.

Immediate medical attention is required for: An erection that lasts longer than 4 hours (priapism), or sudden loss of vision/hearing.

Professional Advice on Using

1. For Spontaneity: Avanafil 50 mg is an ideal choice for men who value spontaneity and do not want to wait an hour for the drug to take effect.

2. Adjustment: If 50 mg is well-tolerated but the effect is insufficient, the dose can be increased to 100 mg.

3. Not for Prolongation: Avanafil does not prolong intercourse and does not treat premature ejaculation.

Avanafil 50 mg: Extended Q&A Section

• How long does Avanafil 50 mg last? The erection effect lasts about 5-6 hours.

• What is the difference between Avanafil 50 mg and Sildenafil 50 mg? Avanafil acts much faster (15-20 min vs 45-60 min) and has a significantly lower risk of vision-related side effects.

• What should I do if 50 mg did not work? Ensure you took the drug and that there was sufficient sexual stimulation. If the effect is insufficient, consult your doctor about switching to 100 mg.

• Does Avanafil prolong sexual intercourse? No. Avanafil is intended only for ED treatment.