Sildenafil 150 mg: Overview of the Increased Dose
Sildenafil 150 mg (e.g., in generics like Cenforce 150, Malegra 150) is a medication containing Sildenafil Citrate (150 mg). This dosage is increased and exceeds the maximum standard daily dose (100 mg). It is important to understand that this tablet is not intended to be taken whole in a single dose in most cases. Its primary purpose is to provide patients with an economical way to obtain standard doses (50 mg or 100 mg) by splitting the tablet.
What is Sildenafil 150 mg and its purpose?
Sildenafil 150 mg is a medication for the treatment of erectile dysfunction (ED) containing 150 mg of Sildenafil.
1. Indication and Dosage Warning
It must be strictly understood: the standard maximum daily dose of Sildenafil approved by regulatory bodies is 100 mg. The 150 mg dosage offered by this drug exceeds this standard.
This medication is intended for:
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Economy: Splitting the 150 mg tablet into 3 parts (50 mg each) or 2 parts (75 mg each) significantly reduces the cost of treatment.
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Severe ED: In rare, resistant cases, where 100 mg has failed, a doctor might (at their discretion and responsibility) recommend trying 150 mg, but this carries an extremely high load on the body.
Mechanism of Action of Sildenafil (150 mg)
The mechanism of action of Sildenafil 150 mg is identical to standard Viagra. It is not an aphrodisiac and does not increase libido.
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Trigger (Stimulation): The drug requires sexual arousal to work.
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NO Release: Arousal causes the release of nitric oxide (NO) in the corpus cavernosum of the penis.
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PDE5 Blockade: Sildenafil blocks the PDE5 enzyme, which degrades cGMP (the substance that relaxes blood vessels).
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Result (Erection): The accumulation of cGMP leads to a powerful inflow of blood to the penis, causing a firm and stable erection.
Key takeaway: Sildenafil 150 mg (even a whole tablet) does not extend the duration of action (it remains 4-6 hours); it only significantly increases the risk of side effects.
Instructions for Using Sildenafil 150 mg: Safety Rules
Taking such a high dose requires extreme caution.
1. Dosing Recommendations (Splitting the Tablet)
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Initial Use: It is strictly forbidden to start treatment with 150 mg. Always start with 1/3 of a tablet (50 mg).
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Standard Maximum Dose: 2/3 of a tablet (100 mg).
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Maximum Daily Dose: Do not take more than 100 mg (2/3 of a tablet) within 24 hours.
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Method: Swallow the required portion of the tablet with water.
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Timing: Take 45–60 minutes before planned sexual activity. The effect lasts 4–6 hours.
2. Influence of Food and Alcohol
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Food: Taking Sildenafil 150 mg with a high-fat meal can significantly delay the onset of action. For the best effect, take it on an empty stomach.
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Alcohol: It is not recommended to combine Sildenafil intake with excessive amounts of alcohol, as this can increase the risk of headaches and hypotension.
Critical Contraindications
The list of contraindications is identical for all forms of Sildenafil.
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Interaction with Nitrates: Absolutely forbidden! Taking Sildenafil 150 mg with any form of organic nitrates (Nitroglycerin) or nitric oxide donors ("poppers") causes a life-threatening drop in blood pressure.
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Severe Cardiovascular Diseases: Recent myocardial infarction or stroke (within 6 months), unstable angina, severe heart failure.
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Blood Pressure: Severe hypotension (pressure < 90/50 mmHg).
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Severe hepatic or renal impairment.
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Eyes: Hereditary degenerative retinal diseases (retinitis pigmentosa).
Side Effects (Increased Risk at 150 mg)
At the 150 mg dose (a whole tablet), side effects are very frequent and can be very pronounced.
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Common: Severe headache, facial flushing, nasal congestion, dyspepsia, pronounced visual disturbances ("blue haze").
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Rare but Dangerous: Priapism (painful erection lasting longer than 4 hours), sudden loss of vision/hearing, severe hypotension.
Professional Advice on Use
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Splitting is the Key to Safety: Sildenafil 150 mg is ideal for splitting. By dividing it into three parts, you get three 50 mg (starting) doses.
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Do not chase the dose: If 100 mg of Sildenafil (2/3 of a tablet) provides a sufficient effect, switching to 150 mg will not provide a significant increase in efficacy but will sharply increase the risk of adverse reactions.
Sildenafil 150 mg: Extended Q&A Section
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How long does Sildenafil 150 mg last? The duration of Sildenafil's action does not depend on the dose. The effect is maintained for 4-6 hours.
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Can I take 150 mg if 100 mg did not work? Moving to such a high dose is possible only after consulting a doctor and ruling out other causes of inefficacy.
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How does Sildenafil 150 mg differ from Sildenafil 100 mg? Only in dosage. It is not a "stronger" drug in terms of effect, but a tablet with a higher concentration, intended for splitting or for patients with severe resistance.
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