MALEGRA DXT

The two most common male sexual problems are erectile dysfunction (ED) and premature ejaculation (PE). MALEGRA DXT is a combination medication designed to address both of these issues simultaneously, offering a balanced formula for efficacy and better tolerability.

What is MALEGRA DXT and its composition?

MALEGRA DXT is a "2-in-1" medication that contains two active ingredients acting on different pathways:

1. Sildenafil Citrate (100 mg): The powerful and proven component (like in Viagra) for achieving and maintaining a firm erection.

2. Duloxetine (30 mg): An effective component for delaying ejaculation and prolonging intercourse.

This combination (100 mg + 30 mg) is considered the "gold standard" for starting combination therapy, as 30 mg of Duloxetine provides a noticeable prolongation effect with a significantly lower risk of side effects than higher doses.

The dual mechanism of action

MALEGRA DXT works on two levels at the same time:

• At the physiological level (Erection): Sildenafil 100 mg is a PDE5 inhibitor. During sexual arousal, it blocks the enzyme responsible for blood outflow from the penis. This causes potent relaxation of blood vessels and maximum filling of the corpus cavernosum with blood, ensuring a reliable erection.

• At the neurogenic level (Ejaculation): Duloxetine 30 mg is a Serotonin-Norepinephrine Reuptake Inhibitor (SNRI). It works in the brain by increasing serotonin concentration. This helps to "put the brakes" on the signal for orgasm, giving the man superior control over ejaculation and significantly increasing the duration of intercourse.

Instructions for using MALEGRA DXT

To achieve maximum effect and ensure safety, strictly follow the intake rules:

1. Dosage: One tablet (100 mg Sildenafil + 30 mg Duloxetine) is the maximum daily dose.

2. Time of Intake: Take one tablet with a full glass of water 60-90 minutes before planned sexual activity. Duloxetine takes longer to activate than Sildenafil.

3. Food: Taking MALEGRA DXT with a high-fat meal can weaken and slow down the action of Sildenafil. It is best taken on an empty stomach.

4. Important: Do not chew or crush the tablet.

Important contraindications for MALEGRA DXT

WARNING! This is a potent combination with strict contraindications.

Taking MALEGRA DXT is strictly prohibited if you:

• Are taking NITRATES (Nitroglycerin, isosorbide dinitrate, etc.). The combination with Sildenafil can cause a fatal drop in blood pressure.

• Are taking MAO Inhibitors (MAOIs) or other antidepressants. The combination with Duloxetine is dangerous and can cause serotonin syndrome.

• Have severe heart, liver, or kidney disease.

• Have had a recent heart attack or stroke (within the last 6 months).

• Have hypotension (low blood pressure).

Possible side effects

The combination can cause side effects from either component. The 30 mg dose of Duloxetine in MALEGRA DXT is better tolerated than 60 mg.

• Common (from Sildenafil): Headache, facial flushing, nasal congestion, "blue haze" in vision.

• Common (from Duloxetine): Nausea (the most common effect), dry mouth, dizziness, drowsiness.

Professional advice on using MALEGRA DT

1. ABSOLUTELY NO ALCOHOL! This is the most important rule. Duloxetine combined with alcohol creates a high risk of toxic liver damage and can cause profound sedation (loss of consciousness, respiratory depression).

2. The Best Start: MALEGRA DXT (100+30) is the ideal option to start combination therapy. Do not start immediately with "PLUS" versions (100+60) unless you are sure that 30 mg is not enough for you.

3. Driving: The medication can cause drowsiness and dizziness. Do not drive until you know how MALEGRA DXTaffects you.

MALEGRA DXT: Answers to common questions

• What is the difference between MALEGRA DXT and MALEGRA DXT PLUS? The dosage of the prolonging agent. MALEGRA DXT has 30 mg of Duloxetine (the standard, milder dose). The "PLUS" version has 60 mg (an enhanced dose).

• What is the difference between MALEGRA DXT and SUPER P-FORCE? The active prolonging agent. MALEGRA DXT uses Duloxetine (an SNRI). Super P-Force uses Dapoxetine (a short-acting SSRI). Duloxetine often provides a longer and more pronounced prolongation effect.

• How long does the effect last? The window of action is 4-6 hours (while the Sildenafil is working), during which time the Duloxetine will provide control over ejaculation.