MALEGRA PRO-50

In the therapy of erectile dysfunction (ED), choosing the starting dose is key to achieving a balance between efficacy and minimizing side effects. MALEGRA PRO-50 is a generic containing 50 mg of Sildenafil Citrate in a sublingual tablet form (for dissolving under the tongue). This combination of dosage and release form makes it an ideal choice for a safe and fast start to treatment.

What is MALEGRA PRO-50?

MALEGRA PRO-50 is an oral medication containing 50 mg of Sildenafil. The distinctive feature of the "Pro" version is the sublingual form (dissolvable tablets).

1. Indication and starting dosage

The 50 mg Sildenafil dose is the "gold standard" and the recommended initial dose for most men first starting ED treatment. MALEGRA PRO-50 is ideally suited for:

• New Users: To assess the efficacy and individual tolerability of Sildenafil.

• Moderate ED: 50 mg is sufficient for 80% of men to achieve a firm erection.

• Risk Reduction: This dose has a significantly lower risk of side effects than 100 mg.

2. Advantage of the sublingual form

The sublingual form (dissolving under the tongue) provides:

• Accelerated Effect: Sildenafil is absorbed directly into the bloodstream through the oral mucosa, bypassing primary metabolism in the liver. The effect can start in as little as 15–25 minutes.

• Independence from the Stomach: Food intake hardly affects the speed of absorption, helping to maintain spontaneity.

• Convenience: The tablet does not need to be washed down with water.

Detailed mechanism of action of MALEGRA PRO-50

The mechanism of action of MALEGRA PRO-50 is based on Sildenafil 50 mg being a PDE5 enzyme inhibitor.

1. Trigger: Sexual arousal causes the release of nitric oxide (NO).

2. Erectile Cycle: NO stimulates the formation of cyclic GMP (cGMP), which relaxes the smooth muscles of the penile blood vessels, ensuring a powerful blood flow.

3. Blockade: Sildenafil blocks the PDE5 enzyme that degrades cGMP. Blocking this enzyme prolongs the action of cGMP, manifold enhancing the natural blood flow and ensuring a stable erection.

Key takeaway: MALEGRA PRO-50 enhances the physiological response but does not cause an erection without sexual arousal.

Instructions for using MALEGRA PRO-50

Strict adherence to the instructions is necessary for the safety and speed of the sublingual form's action.

1. Dosage and method of intake

• Dosage: 50 mg (one tablet) – is the standard single dose. The maximum daily dose is 100 mg.

• Dose Increase: If 50 mg is well-tolerated but the effect is insufficient, the dose can be increased to 100 mg (two tablets) after consulting a doctor.

• Method: Place the MALEGRA PRO-50 tablet under the tongue and hold until fully dissolved. Do not swallow it whole to preserve the advantage of fast absorption.

• Timing: Take 15–25 minutes before planned activity.

2. Influence of food and alcohol

• Food: Taking it on an empty stomach guarantees the fastest effect.

• Alcohol: It is not recommended to combine Sildenafil intake with alcohol, as this enhances the vasodilating effect, increasing the risk of headaches and hypotension.

Critical contraindications for MALEGRA PRO-50

The list of contraindications must be reviewed with a doctor.

• Interaction with Nitrates: Absolutely forbidden! Taking MALEGRA PRO-50 with any form of organic nitrates (Nitroglycerin) or nitric oxide donors ("poppers") causes a life-threatening drop in blood pressure.

• Severe Cardiovascular Diseases: Recent heart attack or stroke (within 6 months), unstable angina, severe heart failure.

• Blood Pressure: Persistent hypotension (pressure < 90/50 mmHg) or uncontrolled hypertension.

• Liver and Kidneys: Severe hepatic or renal failure.

• Eyes: Hereditary degenerative retinal diseases (retinitis pigmentosa).

Side effects of MALEGRA PRO-50 (Low Risk)

The 50 mg dosage has a good safety profile, and side effects occur less frequently than at 100 mg.

• Common: Headache (the most frequent effect), facial flushing, nasal congestion.

• Less Common: Mild visual disturbance (change in color perception), dyspepsia, dizziness.

Immediate medical attention is required for: An erection that lasts longer than 4 hours (priapism), or sudden loss of vision/hearing.

Professional advice on using MALEGRA PRO-50

1. Speed and Spontaneity: The sublingual form makes MALEGRA PRO-50 an ideal choice for situations requiring fast and discreet intake, without the need to find water.

2. Dosing Flexibility: The tablet can be split in half to obtain a minimum 25 mg dose for assessing sensitivity.

3. Hydration: To minimize headaches, drinking enough water on the day of intake is recommended.

MALEGRA PRO-50: Extended Q&A section

• How much faster is MALEGRA PRO-50 than a regular Sildenafil 50 mg tablet? Thanks to sublingual absorption, the effect can start 20–40 minutes faster than if swallowed.

• How long does MALEGRA PRO-50 last? The duration of action of Sildenafil 50 mg averages 4-6 hours. The release form affects speed but not duration.

• What is the difference between MALEGRA PRO-50 and FILDENA CT 50? Both drugs contain 50 mg of Sildenafil and are designed for rapid absorption through the oral cavity (sublingual/chewable). They are analogues with identical efficacy and speed.

• Do I need to take 100 mg if 50 mg helped? No. Take the minimum effective dose (50 mg) to avoid unnecessary side effects.