Buy Cialis 20 mg in Ukraine

Cialis 20 mg: "The Weekend Pill" – A Complete Medical Review

Cialis 20 mg is the original, brand-name medication whose active pharmaceutical ingredient is Tadalafil (20 mg). This medication is known worldwide as "the weekend pill" due to its unique duration of action—up to 36 hours. The 20 mg dosage is the maximum standard dose, intended for men who require a guaranteed and long-lasting effect in the treatment of erectile dysfunction (ED).

What is Cialis 20 mg and its key advantage?

Unlike Sildenafil (Viagra) or Vardenafil (Levitra), which last an average of 4-6 hours, Cialis 20 mg provides a "window of readiness" for up to 36 hours.

This is precisely why it is nicknamed "the weekend pill." It means that after taking one tablet, a man does not need to worry about planning sex "by the clock." For up to one and a half days, he can achieve an erection at any moment in response to sexual stimulation. This brings spontaneity and naturalness back into relationships, eliminating the psychological discomfort associated with needing to take a pill right before the act.

Detailed Mechanism of Action of Cialis

The mechanism of action of Tadalafil is vascular. It does not affect libido (desire) or brain chemistry.

1. Trigger (Stimulation): The drug requires sexual arousal to work. During arousal, nerve endings in the penis release nitric oxide (NO).

2. Erectile Cycle: NO activates an enzyme that produces cyclic GMP (cGMP). cGMP is the key substance that relaxes the smooth muscles of the blood vessels in the corpus cavernosum.

3. Result (Engorgement): This relaxation allows the vessels to widen, leading to a powerful inflow of blood and an erection.

4. PDE5 Blockade: Normally, the PDE5 enzyme quickly breaks down cGMP, and the erection subsides. Tadalafilblocks this enzyme. This allows cGMP to accumulate and last longer, ensuring a stable and firm erection.

Key takeaway: Cialis 20 mg is not an aphrodisiac and does not cause a spontaneous erection. It only enhances the natural physiological response to sexual stimulation.

Indications for Use

Tadalafil has two main, clinically proven indications:

1. Erectile Dysfunction (ED): The inability to achieve or maintain an erection.

2. Benign Prostatic Hyperplasia (BPH): Also known as an "enlarged prostate."

The 20 mg dosage is intended exclusively for the "on-demand" treatment of ED.

Instructions for Use and Dosage

There are two fundamentally different regimens for taking Tadalafil. Cialis 20 mg is used only for the first regimen.

Regimen 1: "On-Demand" Use (10 mg and 20 mg)

This regimen is used by men who have sex infrequently and want a guaranteed, long-lasting effect.

• Cialis 10 mg (Starting Dose): The recommended initial dose. It is sufficient for most men and carries a lower risk of side effects.

• Cialis 20 mg (Maximum Dose): (e.g., Vidalista 20, Tadacip 20). Prescribed if 10 mg proves to be insufficient.

• Time of Intake: 30-60 minutes before sexual activity.

• Frequency: No more than once every 24-36 hours.

Regimen 2: "Daily Use" (5 mg)

For this regimen, Cialis 5 mg is used. The 20 mg dose is categorically unsuitable for daily use.

Influence of Food and Alcohol

• Food: Tadalafil is the only PDE5 inhibitor whose effectiveness is virtually unaffected by food, including fatty meals.

• Alcohol: It is considered the most alcohol-compatible drug in its class. Moderate doses of alcohol (e.g., a glass of wine) do not usually reduce efficacy. However, excessive consumption can increase the risk of dizziness and hypotension.

Critical Contraindications

The list of contraindications related to the vasodilating effect is strict.

• Interaction with Nitrates: Absolutely forbidden! Taking Tadalafil with any form of organic nitrates (Nitroglycerin, isosorbide dinitrate) or nitric oxide donors ("poppers") causes a life-threatening drop in blood pressure.

• Severe Cardiovascular Diseases: Recent heart attack or stroke (within 6 months), severe heart failure, unstable angina.

• Blood Pressure: Persistent hypotension (pressure < 90/50 mmHg) or uncontrolled hypertension.

• Severe hepatic or renal impairment.

• History of vision loss due to Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION).

Side Effects of Cialis 20 mg

Cialis 20 mg is well-tolerated but has its own unique set of side effects, different from Sildenafil.

• Common: Headache, dyspepsia (indigestion), facial flushing, nasal congestion.

• Specific to Tadalafil: Back pain and myalgia (muscle aches). These effects are usually mild, related to PDE11 inhibition in muscles, and resolve within 12–48 hours.

• Visual Risk: Tadalafil has almost no effect on PDE6 in the retina, so it does not cause color vision disturbances ("blue haze"), unlike Sildenafil.

Innovative Release Forms (Generics)

Besides the original Cialis 20 mg, Indian generics (Tadalista, Tadarise, Vidalista) offer:

• Soft (Chewable/Sublingual): (Tadalista CT, Tadarise PRO). Start working faster (15-25 minutes) due to absorption in the mouth.

• Oral Jelly: (Tadarise Oral Jelly). Have the same rapid onset and are convenient for those who have difficulty swallowing pills.

• High Doses (40, 60, 80 mg): (Vidalista 40/60/80). Intended only for splitting for economic reasons.

Conclusion: Cialis vs. Viagra

• Cialis (Tadalafil): Your choice if you need spontaneity and duration (up to 36 hours). Ideal for a weekend.

• Viagra (Sildenafil): Your choice if you need a powerful, but short and predictable effect (4-6 hours).