ZHEWITRA 60

In the treatment of severe erectile dysfunction (ED), there is sometimes a need for a dosage exceeding the standard maximum. ZHEWITRA 60 is a generic containing a very high concentration of the active component Vardenafil (60 mg). This medication is intended exclusively for men suffering from severe or resistant ED who have not received an adequate response from the 20 mg dose.

What is ZHEWITRA 60?

ZHEWITRA 60 is an oral tablet medication containing 60 mg of Vardenafil. Vardenafil is a highly selective PDE5 inhibitor.

1. Indication and dosage warning

It must be strictly understood: the standard maximum daily dose of Vardenafil recommended by official bodies is 20 mg. The 60 mg dosage offered by ZHEWITRA 60 significantly exceeds this norm and carries increased risks.

ZHEWITRA 60 should never be used as a starting or standard dose. It is intended only for:

• Patients in whom 20 mg of Vardenafil proved ineffective.

• Men with extremely low response to Vardenafil due to severe vascular impairments (e.g., severe diabetes).

• Use under strict medical supervision for dose splitting.

Detailed mechanism of action of ZHEWITRA 60

The mechanism of action of ZHEWITRA 60 is based on Vardenafil blocking the PDE5 enzyme with high selectivity.

1. Trigger: Sexual arousal causes the release of nitric oxide (NO).

2. Erectile Cycle: NO stimulates the formation of cyclic GMP (cGMP), which relaxes the smooth muscles of blood vessels, causing a powerful blood flow.

3. PDE5 Blockade: Vardenafil 60 mg provides maximum inhibition of the PDE5 enzyme. The increased dose is aimed at overcoming resistance in patients with severe blood flow impairments, ensuring a firm and stable erection.

Key takeaway: Vardenafil in ZHEWITRA 60 requires sexual arousal for activation and does not affect the duration of intercourse.

Instructions for using ZHEWITRA 60: Safety rules

Taking a dose as high as 60 mg is associated with serious risks.

1. Dosing recommendations

• Initial Use: It is strictly forbidden to start treatment with 60 mg! Always start with 1/6 of a tablet (10 mg) or 1/3 of a tablet (20 mg).

• Maximum Daily Dose: 60 mg is the absolute maximum. You must not take more than one ZHEWITRA 60 tablet within 24 hours.

• Practicality: The most sensible use of ZHEWITRA 60 is to split it into three standard maximum doses of 20 mg.

• Method: Swallow the tablet whole with water, 30–60 minutes before sexual intercourse.

2. Interaction with food and alcohol

• Food: Vardenafil is well-tolerated with food, but for maximum effect, it is best taken on an empty stomach.

• Alcohol: Not recommended. Taking 60 mg of Vardenafil and alcohol can sharply increase side effects, including hypotension (sudden drop in pressure), which is dangerous.

Critical contraindications for ZHEWITRA 60

Due to the potentially high risk, the list of contraindications must be strictly observed.

• Interaction with Nitrates: Absolutely forbidden! Taking ZHEWITRA 60 with nitrates or nitric oxide donors (e.g., Nitroglycerin) causes a life-threatening drop in blood pressure.

• Severe Cardiovascular Diseases: Recent heart attack or stroke (within 6 months), unstable angina, severe heart failure.

• Blood Pressure: Persistent hypotension (pressure < 90/50 mmHg) or uncontrolled hypertension.

• Liver and Kidneys: Severe hepatic or renal failure.

Side effects of ZHEWITRA 60: Increased Risk

At the 60 mg Vardenafil dosage, the probability and intensity of side effects increase manifold compared to 20 mg.

• Very Common: Severe headache, pronounced facial flushing, nasal congestion.

• Common: Dizziness, dyspepsia (indigestion), back and muscle pain (myalgia).

• Increased Risk of Serious Effects: Priapism (painful erection lasting longer than 4 hours), sudden loss of vision or hearing, severe hypotension.

Professional advice on using ZHEWITRA 60

1. Pill Splitting is the key to safety and economy: ZHEWITRA 60 should be used as a source of 10 mg or 20 mg doses. By dividing it into three parts, you get three maximum standard doses of 20 mg, which is safe and economically advantageous.

2. Medical Control: If you truly require a dose exceeding 20 mg, this is a serious indication for a thorough cardiovascular examination.

3. Assess Necessity: A higher dose of ZHEWITRA 60 will not prolong the drug's action (it remains 4–6 hours); it will only increase the strength of the effect and the risks of adverse reactions.

ZHEWITRA 60: Extended Q&A section

• How much stronger is 60 mg of Vardenafil than 20 mg? The increase in efficacy is not linear. The primary effect is achieved at 20 mg. The 60 mg dose is intended for overcoming resistance, not for achieving a "super-effect."

• How long does ZHEWITRA 60 last? The duration of action of Vardenafil 60 mg averages 4-6 hours.

• How does ZHEWITRA 60 differ from LOVEVITRA 60? They are direct generics with identical active substance and dosage. The difference is only in the trade name.

• Should I take 60 mg if 20 mg did not work? The transition to 60 mg should only be considered after consulting a doctor and ruling out incorrect intake (e.g., with a fatty meal) or other medical causes.