TADAGRA 20

TADAGRA 20 is a high-quality generic containing Tadalafil (20 mg). This medication is known worldwide as "the weekend pill" due to its unique duration of action—up to 36 hours. The 20 mg dosage is the maximum standard dose, intended for men who require a guaranteed and long-lasting effect in the treatment of erectile dysfunction (ED).

What is TADAGRA 20 and its main advantage?

TADAGRA 20 is an Indian generic that is a complete analogue of the original "Cialis" medication. Its active substance is Tadalafil.

The main advantage of TADAGRA 20 is its unprecedented duration of action. Unlike Sildenafil (4-6 hours) or Vardenafil (4-6 hours), Tadalafil provides a "window of readiness" for up to 36 hours. This means that after taking one tablet, a man can achieve an erection in response to sexual stimulation at any moment within one and a half days, completely eliminating the need to plan sex "by the clock" and restoring spontaneity to relationships.

Mechanism of action of TADAGRA 20 (Tadalafil)

TADAGRA 20 is a selective inhibitor of the PDE5 enzyme (phosphodiesterase type 5).

1. Trigger: The mechanism is triggered only in the presence of sexual stimulation, which causes the release of nitric oxide (NO).

2. Erectile Cycle: NO stimulates the formation of cyclic GMP (cGMP), which relaxes the smooth muscles of the penile blood vessels, ensuring a powerful blood flow.

3. Blockade: Tadalafil blocks the PDE5 enzyme that degrades cGMP. Blocking this enzyme allows cGMP to persist longer, ensuring a stable, firm erection.

Key takeaway: TADAGRA 20 does not cause a spontaneous erection. It only works in the presence of natural sexual arousal, but it does so for up to 36 hours.

Instructions for using TADAGRA 20

Strict adherence to the instructions is necessary, considering the high dosage and long duration of action.

1. Dosage and timing of intake

• Dosage: 20 mg (one tablet) – is the maximum recommended daily dose for "on-demand" use.

• Frequency of Intake: It is strictly prohibited to take more than one TADAGRA 20 tablet within 24–36 hours due to its long half-life.

• Initial Dose: If you are trying Tadalafil for the first time, it is recommended to start with 10 mg (half a tablet).

• Method: Swallow the tablet whole with water.

• Timing: Take 30–60 minutes before planned sexual activity.

2. Influence of food and alcohol

• Food: TADAGRA 20 can be taken regardless of food intake, including moderately fatty food, which is its advantage.

• Alcohol: Tadalafil is considered the most alcohol-friendly drug in its class. Moderate alcohol consumption usually does not reduce efficacy, however, excessive consumption can increase the risk of dizziness.

Critical contraindications

The list of contraindications related to the vasodilating effect is strict.

• Interaction with Nitrates: Absolutely forbidden! Taking TADAGRA 20 with any form of organic nitrates (Nitroglycerin) or nitric oxide donors ("poppers") causes a life-threatening drop in blood pressure.

• Severe Cardiovascular Diseases: Recent heart attack or stroke (within 6 months), unstable angina, severe heart failure.

• Blood Pressure: Persistent hypotension (pressure < 90/50 mmHg) or uncontrolled hypertension.

• Liver and Kidneys: Severe hepatic or renal failure.

• Eyes: Hereditary degenerative retinal diseases (retinitis pigmentosa), history of NAION.

Side effects of TADAGRA 20 mg

TADAGRA 20 is well-tolerated but has its unique set of side effects.

• Common: Headache, dyspepsia (indigestion), facial flushing, nasal congestion.

• Specific to Tadalafil: Back pain and myalgia (muscle aches). These effects are usually mild and pass within 12–24 hours.

• Visual Risk: Tadalafil rarely causes color vision disturbances ("blue haze"), unlike Sildenafil.

Professional advice on using TADAGRA 20

1. Dosing Flexibility: Start with half a tablet (10 mg). If this dose is sufficient, there is no need to take 20 mg and increase the risks of side effects.

2. Not for daily use: The 20 mg dose is intended for "on-demand" use. Doses of 2.5 mg or 5 mg are used for daily therapy.

3. Alternative: If you need a fast but short effect (4-6 hours), consider Sildenafil or Vardenafil.

TADAGRA 20: Extended Q&A section

• How does TADAGRA 20 differ from Sildenafil 100 mg? The main difference is duration. Sildenafil lasts 4–6 hours; TADAGRA 20 lasts up to 36 hours.

• How long does TADAGRA 20 last? The effect lasts up to 36 hours.

• Can I take TADAGRA 20 if I don't have ED? The drug is intended only for the treatment of ED. Intake without indication can lead to unnecessary side effects.

• Does TADAGRA 20 prolong sexual intercourse? No. Tadalafil is intended only for ED treatment and does not affect the time to ejaculation. Medications containing Dapoxetine are used for prolongation.