Buy Dapoxetine 30 mg in Ukraine

Dapoxetine 30 mg: The Starting Dose for Premature Ejaculation (PE) Control

Dapoxetine 30 mg (e.g., in generics like Poxet 30, Vriligy 30) is a medication containing the recommended starting dose of Dapoxetine Hydrochloride. It is the only active ingredient specifically designed and clinically approved for the treatment of premature ejaculation (PE) in men aged 18 to 64.

It is important to understand that Dapoxetine does not treat erectile dysfunction (ED) and does not affect erection hardness. Its sole purpose is ejaculation control.

What is Dapoxetine and its indication?

Dapoxetine is a medication for "on-demand" use. Unlike traditional antidepressants, it belongs to the Selective Serotonin Reuptake Inhibitor (SSRI) class, but it has an ultra-short half-life (about 1.5–2 hours).

1. Indication and the 30 mg Dosage

The drug is indicated exclusively for the treatment of PE.

• 30 mg Dose (Starting): This is the recommended initial dose for most men. It provides an optimal balance between efficacy (allows for a 2-3 fold increase in intercourse duration) and a low risk of side effects.

• 60 mg Dose (Maximum): Used only if 30 mg was insufficient and the drug was well-tolerated.

Detailed Mechanism of Action of Dapoxetine

The mechanism of action of Dapoxetine is centered on the neurochemical processes in the central nervous system that regulate the ejaculation reflex.

1. Serotonin: Ejaculation is controlled by a complex chain of reflexes where serotonin (5-HT) plays a key inhibitory role. Low serotonin activity is associated with rapid ejaculation.

2. Action of Dapoxetine: Dapoxetine blocks the transporter proteins that carry out the reuptake of serotonin in neurons. This leads to a temporary and rapid increase in serotonin concentration in the synaptic cleft.

3. Result: The enhanced serotonergic transmission exerts an inhibitory effect on the brain and spinal cord centers that control ejaculation. This slows down nerve impulses and allows the man to significantly prolong sexual intercourse.

Key takeaway: The ultra-short action of Dapoxetine allows it to be taken "on-demand," without the drug accumulating in the body, which is typical of conventional SSRIs.

Instructions for Using Dapoxetine (30 mg)

Strict adherence to the rules for taking Dapoxetine 30 mg is critical to minimizing side effects, especially the risk of fainting (syncope).

1. Dosage and timing of intake

• Dosage: 30 mg (one tablet) – is the starting dose. Do not take more than one tablet per day.

• Method: Swallow the tablet whole with a full glass (at least 250 ml) of water. Do not chew.

• Timing: Take 1–3 hours before planned sexual activity.

2. Influence of Alcohol

• Alcohol: ABSOLUTE PROHIBITION. Combining Dapoxetine with alcohol manifold increases the risk of neurocognitive side effects (dizziness, drowsiness, sluggishness) and can lead to fainting (syncope).

Critical Contraindications

The list of contraindications related to the drug's neurochemical action is very strict.

• Cardiovascular Disorders: Cardiac rhythm disturbances (blocks, bradycardia), severe heart failure, IHD.

• Hepatic Impairment: Severe and moderate severity.

• Psychiatric Disorders: History of mania, severe depression, uncontrolled bipolar disorder.

• Drug Interactions: Absolutely forbidden to take with:

  • MAO Inhibitors (MAOIs): Risk of serotonin syndrome.

  • Potent CYP3A4 Inhibitors: (Ketoconazole, Erythromycin, Grapefruit juice).

  • Other SSRIs: (Antidepressants).

Side Effects (Risk at 30 mg)

At the 30 mg dose, side effects are less frequent and usually milder than at 60 mg.

• Common: Nausea (the most common side effect, but less pronounced than at 60 mg), dizziness, headache.

• Less Common: Drowsiness, diarrhea, dry mouth.

• Risk: Fainting (syncope) due to orthostatic hypotension. This risk is minimal at 30 mg but still exists.

Professional Advice on Using

1. Start with 30 mg: Dapoxetine 30 mg is the correct and safe starting dose. Do not start with 60 mg, even if it seems "more effective."

2. Take with water, while sitting: To minimize the risk of fainting, always take the drug while standing or sitting, washing it down with a full glass of water, and avoid standing up abruptly.

3. Combination Therapy: If you have both PE and ED, Dapoxetine 30 mg can be combined with PDE5 inhibitors (e.g., Sildenafil 50 mg or Tadalafil 10 mg).

Dapoxetine 30 mg: Extended Q&A Section

• How much does Dapoxetine 30 mg prolong intercourse? On average, IELT (latency time) increases by 2.5–3 times.

• How soon does Dapoxetine 30 mg start working? The effect begins after 60 minutes, with the peak effect occurring 1–2 hours after intake.

• How does Dapoxetine differ from delay sprays (Lidocaine)? Dapoxetine (pills) works "from the inside" via the brain, maintaining full sensitivity. Sprays (Lidocaine) work "from the outside," causing numbness and mechanically reducing sensitivity.