LOVEVITRA 60

In the treatment of erectile dysfunction (ED), situations exist where standard doses of PDE5 inhibitors prove ineffective. LOVEVITRA 60 is a generic containing a very high concentration of the active component Vardenafil (60 mg). This medication is intended exclusively for men with severe and resistant forms of ED who require an elevated concentration of the substance to achieve a therapeutic response.

What is LOVEVITRA 60?

LOVEVITRA 60 is a highly concentrated, Indian-manufactured medication containing 60 mg of Vardenafil.

1. Peculiarities of the 60 mg dosage

It must be immediately emphasized: the standard maximum daily dose of Vardenafil recommended by official health bodies is 20 mg. The 60 mg dosage offered by LOVEVITRA 60 significantly exceeds this norm.

This drug should never be used as a first or standard dose. It is only intended for those who:

• Suffer from a very severe form of ED, for example, after complex pelvic surgery.

• Have low sensitivity to Vardenafil or other PDE5 inhibitors.

• Use it under strict medical supervision for titrating the minimum effective dose.

Detailed mechanism of action of Vardenafil

Vardenafil, the active component of LOVEVITRA 60, is a highly selective inhibitor of the PDE5 enzyme. Its mechanism of action ensures a powerful and stable erection in response to sexual stimulation.

1. Trigger: Sexual arousal triggers the release of nitric oxide (NO).

2. NO-cGMP Cycle: NO initiates the synthesis of cyclic Guanosine Monophosphate (cGMP). cGMP relaxes smooth muscles, widening the arteries in the penis.

3. PDE5 Blockade: The PDE5 enzyme breaks down cGMP, concluding the erection. Vardenafil blocks PDE5, allowing cGMP to persist longer in the tissues. The increased 60 mg dose aims for maximum PDE5 inhibition even in cases of severe blood flow impairment.

Important to remember: LOVEVITRA 60 does not cause an erection spontaneously. Full sexual stimulation is required for it to work.

Instructions for using LOVEVITRA 60: Safety rules

Taking a dose as high as 60 mg is associated with increased risks, so utmost caution is required.

1. Dosing recommendations

• Initial Use: It is strictly forbidden to take a whole 60 mg tablet as an initial dose. Always start with 1/6 of a tablet (10 mg) or 1/3 of a tablet (20 mg).

• Maximum Daily Dose: 60 mg is the absolute maximum. You must not take more than one LOVEVITRA 60 tablet within a 24-hour period.

• Method of Intake: Swallow the tablet whole with water, 30-60 minutes before sexual intercourse.

• Practicality: The sensible use of LOVEVITRA 60 is to view it as a source of three standard maximum doses of 20 mg.

2. Interaction with food and alcohol

• Food: Vardenafil is considered one of the least food-dependent PDE5 inhibitors. However, a high-fat meal can delay the onset of action.

• Alcohol: Although Vardenafil is better tolerated with alcohol than Sildenafil, taking a high dose of LOVEVITRA 60 and alcohol is not recommended. This combination can sharply intensify side effects, including hypotension and dizziness.

Critical contraindications for LOVEVITRA 60

Due to the potentially high risk, the list of contraindications must be strictly observed.

• Interaction with Nitrates: Absolutely forbidden to take LOVEVITRA 60 with nitrates or nitric oxide donors (e.g., Nitroglycerin). This combination can cause a fatally dangerous drop in blood pressure.

• Cardiovascular Diseases: Recent heart attack or stroke (within 6 months), unstable angina, severe heart failure (NYHA Class III or IV).

• Hypotension and Arrhythmia: Persistent low blood pressure (below 90/50 mmHg) and severe forms of arrhythmia.

• Liver and Kidneys: Severe liver impairment (Child-Pugh Class C) or kidney failure requiring dialysis.

• Eyes: Hereditary retinal diseases (retinitis pigmentosa) or recent vision loss due to NAION.

Side effects of LOVEVITRA 60: Increased Risk

At the 60 mg dosage, the probability and intensity of side effects increase manifold compared to the maximum recommended dose of 20 mg.

• Very Common: Severe headache, pronounced facial flushing, nasal congestion.

• Common: Dizziness, dyspepsia (upset stomach), back pain.

• Increased Risk of Serious Effects: Vardenafil can affect the QT interval. Priapism (painful erection lasting longer than 4 hours), sudden loss of vision or hearing, severe hypotension.

Professional advice on using LOVEVITRA 60

1. Pill Splitting: The LOVEVITRA 60 tablet should be viewed as a source of three 20 mg doses or six 10 mg doses. Do not use it for a single 60 mg dose if 20 mg is already providing an effect.

2. Cardiology Consultation: If you require a dose exceeding 20 mg, this is a serious indication for a thorough cardiovascular examination.

3. Do Not Chase Strength: Taking 60 mg does not mean the erection will last longer than 4-6 hours. The duration of Vardenafil's action is fixed and does not depend on the dose. Increasing the dose only affects the strength of the effect and the risks of side effects.

LOVEVITRA 60: Extended Q&A section

• How much stronger is 60 mg of Vardenafil than 20 mg? Pharmacological studies show that the effect does not increase linearly. The majority of the therapeutic effect is achieved at 20 mg. The 60 mg dose is intended for overcoming resistance, not for achieving a "super-effect."

• Why do manufacturers produce a 60 mg dose if the maximum recommended is 20 mg? Dosages like 60 mg or 40 mg are produced by generic companies for men with extremely low response to standard doses (severe forms of diabetes or after radical prostatectomy) who require a high concentration of the substance. However, this should only be done following an individualized regimen.

• Can LOVEVITRA 60 cause hearing or vision problems? Like all PDE5 inhibitors, Vardenafil carries a very small risk of sudden vision or hearing loss. Taking 60 mg increases this risk. If any visual or auditory disturbances occur, discontinue use immediately.

• How long after eating can I take LOVEVITRA 60? For the fastest and most reliable effect, it is best taken on an empty stomach. If you have eaten, wait 2-3 hours for the stomach to empty.